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Welcome to Clinical Global Frontiers

Clinical Global Frontiers (CGF) is a Filipino-owned company established by Victor Arni Sicam, PhD – a Filipino Scientist who developed a new technology in corneal imaging, which was granted European and US patents. We specialize in Ophthalmic Equipment and Devices having the most advanced technology on the market, making it available to the Filipino community.

Meet the Inventor

Victor Arni Sicam, PhD

Victor Arni Sicam, PhD

In 2007, I obtained PhD in Medical Physics at the VU University Medical Centre in Amsterdam. During my PhD studies I was able to develop a new technology in corneal imaging that eventually was granted European and US patents. This technology was later adopted by a start-up company, i-Optics, who developed the product and brought the novel corneal shape analyser, the Cassini, to the world market. As a pioneer in i-Optics I was involved in many aspects of the work including maintaining patent portfolio; organizing, designing and implementing clinical trials to the support the claims of the product; being active also in product development especially in developing new software features for the product. In the process, I was involved in scientific and commercial publications. It has brought me great accomplishment to experience the whole process “from bench to bedside” of applied technology in medicine.

To supplement my activities in i-Optics, I worked as a senior researcher at the Rotterdam Ophthalmic Institute of the Rotterdam Eye Hospital. I led a 2 year project funded by NutsOhra from 2012-2014 “Towards spectacle free outcomes in cataract refractive surgery”. This project produced results which were useful in promoting superior corneal diagnostics for astigmatism correction in refractive surgery. It also served as a catalyst to motivate multi-center studies on the Cassini which was presented in Ophthalmology Congresses in the US as well as in Europe. I also collaborated with the Optical Coherence Tomography group led by Johannes de Boer.

PhD in Medical Physics
VU University Medical Center, Amsterdam, The Netherlands

MS Physics (Valedictorian)
University of the Philippines, Diliman, Quezon City

BS Physics (Cum Laude / Best Undergraduate Thesis)
University of the Philippines, Diliman, Quezon City

Cassini BV,  Den Haag, The Netherlands  (formerly i-Optics BV)

 Principal Research Scientist                                              2008 – 1 March 2016

  • Designed and implemented clinical trials
  • Manager of patent portfolio
  • Managed scientific publications portfolio

Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands

 Senior Research Physics                                                    October 2008 – January 2015

  • Post doc research on optical coherence tomography under the supervision of Johannes de Boer
  • Research on optical aberration of the eye and its applications in Cataract Surgery, Laser Surgery and Corneal Diagnostics
  • Supervision of PhD Students
  • Managed 2 year project funded by NutsOhra “Towards Spectacle Free Outcomes in Cataract Refractive Surgery”

VU University Medical Center, Amsterdam, The Netherlands

Post Doctoral Research                                                      January 2007 – August 2008

PhD Studies                                                                           January 2002 – January 2007

Title of Dissertation:

Optical properties of the human cornea: shape and  wave aberration measurements using the VU topographer and Scheimpflug photography.

  • Klijn S, Reus NJ, van der Sommen CM, Sicam VA.
    • Accuracy of Total Corneal Astigmatism Measurements With a Scheimpflug Imager and a Color Light-Emitting Diode Corneal Topographer. Am J Ophthalmol. 2016 Jul;167:72-8.
  • Klijn, S., van der Sommen, C. M., Sicam, V. A. D. P. and Reus, N. J. (2016),
    • Value of posterior keratometry in the assessment of surgically induced astigmatic change in cataract surgery. Acta Ophthalmol, 94: 494–498.
  • Klijn S, Sicam VA, Reus NJ.
    • Long-term changes in intraocular lens position and corneal curvature after cataract surgery and their effect on refraction. J Cataract Refract Surg. 2016 Jan;42(1):35-43.
  • Endl MJ, Friess DW, Sicam VA, Kugler L.
    • New Technologies in Anterior Segment Diagnostic Assessment for Refractive Lens Exchange. Chapter 5 of Refractive Lens Exchange: A Surgical Treatment for Presbyopia ed. Wang MX, Thorofare, New Jersey: Slack Inc. © 2016.
  • Klijn S, Reus NJ, Sicam VA.
    • Evaluation of keratometry with a novel Color-LED corneal topographer. J Refract Surg. 2015 Apr;31(4):249-56.
  • Hillenaar T, Sicam VA, Vermeer KA, Braaf B, Remeijer L, Cals RH, de Boer JF.
    • Wide-range calibration of corneal backscatter analysis by in vivo confocal microscopy. Invest Ophthalmol Vis Sci. 2011 Apr 5;52(5):2136-46.
  • Braaf B, Vermeer KA, Sicam VA, van Zeeburg E, van Meurs JC, de Boer JF.
    • Phase-stabilized optical frequency domain imaging at 1-µm for the measurement of blood flow in the human choroid. Opt Express. 2011 Oct 10;19(21):20886-903.
  • Snellenburg JJ, Braaf B, Hermans EA, van der Heijde RG, Sicam VA.
    • Forward ray tracing for image projection prediction and surface reconstruction in the evaluation of corneal topography systems. Opt Express. 2010 Aug 30;18(18):19324-38.
  • Vrijling AC, Braaf B, Snellenburg JJ, de Lange F, Zaal MJ, van der Heijde RG, Sicam VA.
    • Clinical validation of point-source corneal topography in keratoplasty. Optom Vis Sci. 2011 Jul;88(7):E837-42.
  • Braaf B, van de Watering TC, Spruijt K, van der Heijde RGL & Sicam VADP.
    • Calculating Angle Lambda (λ) Using Zernike Tilt Measurements in SpecularReflection Corneal Topography. Journal of Optometry 2: 201-214, 2009.
  • Braaf B, Dubbelman M, van der Heijde RG, Sicam VA.
    • Performance in specular reflection and slit-imaging corneal topography. Optometry and Vision Science 86(5): 467-75, 2010
  • Sicam VADP, Snellenburg JJ, van der Heijde RGL & van Stokkum IHM.
    • Pseudo forward ray-tracing validation in corneal topography. Optometry and Vision Science 84(9): 915-23, 2007.
  • Dubbelman M, Sicam VADP & van der Heijde RGL.
    • The contribution of the posterior surface to the coma aberration of the human cornea. Journal of Vision 7(7): Article 10 Pages 1-8 2007.
  • Sicam VADP & van der Heijde.
    • Topographer reconstruction of the non- rotation-symmetric anterior corneal surface features. Optometry and Vision Science 83: 910- 918, 2006.
  • Sicam VADP, Dubbelman M & van der Heijde RGL.
    • Spherical aberration of the anterior and posterior surfaces of the human cornea. Journal of the Optical Society of America A 23(3): 544-549, 2006.
  • Dubbelman M, Sicam VA & van der Heijde GL.
    • The shape of the anterior and posterior surfaces of the human cornea. Vision Research 46(6-7) 2006.
  • Sicam VADP, Coppens J, van den Berg TJTP & van der Heijde RGL.
    • Corneal surface reconstruction algorithm that uses Zernike polynomial representation. Journal of the Optical Society of America A 21(7): 1300-1306, 2004.

References: Available  on request

Updated: 09/08/2017

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OUR EXPERTISE

We maintain the highest level of expertise for each product we select. Our medical technological skills, product research, and after-sales support are the core competencies of our company which enable us to deliver the best technology in the eye care industry. This also ensures the doctors’ confidence in surgical outcomes and gives value for money for their patients.

Our Mission

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“To provide the most advanced technology in the Eye Care Industry”

Our Vision

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To build a strong collaborative partnership with our industry peers and healthcare providers towards giving the Filipino community the products that can deliver the best visual outcomes. As we are determined to be the best in the business, we maintain a high level of knowledge, innovation, and technical expertise in our people to deliver integrated solutions for our partners and clients. We will continue to bring our industry nuances of style and a steadfast approach to the eye care business, which are consistent with our evolving aspirations.

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